Journal article
Rachel E. Busselman, Alyssa C. Meyers, Italo B Zecca, L. Auckland, Andres H Castro, Rebecca E Dowd, R. Curtis-Robles, C. Hodo, A. Saunders, S. Hamer
PLoS neglected tropical diseases, 2021
PLoS neglected tropical diseases, 2021
Semantic Scholar
DOI
PubMedCentral
PubMed
Cite
Cite
APA
Click to copy
Busselman, R. E., Meyers, A. C., Zecca, I. B., Auckland, L., Castro, A. H., Dowd, R. E., … Hamer, S. (2021). High incidence of Trypanosoma cruzi infections in dogs directly detected through longitudinal tracking at 10 multi-dog kennels, Texas, USA. PLoS Neglected Tropical Diseases.
Chicago/Turabian
Click to copy
Busselman, Rachel E., Alyssa C. Meyers, Italo B Zecca, L. Auckland, Andres H Castro, Rebecca E Dowd, R. Curtis-Robles, C. Hodo, A. Saunders, and S. Hamer. “High Incidence of Trypanosoma Cruzi Infections in Dogs Directly Detected through Longitudinal Tracking at 10 Multi-Dog Kennels, Texas, USA.” PLoS neglected tropical diseases (2021).
MLA
Click to copy
Busselman, Rachel E., et al. “High Incidence of Trypanosoma Cruzi Infections in Dogs Directly Detected through Longitudinal Tracking at 10 Multi-Dog Kennels, Texas, USA.” PLoS Neglected Tropical Diseases, 2021.
BibTeX Click to copy
@article{rachel2021a,
title = {High incidence of Trypanosoma cruzi infections in dogs directly detected through longitudinal tracking at 10 multi-dog kennels, Texas, USA},
year = {2021},
journal = {PLoS neglected tropical diseases},
author = {Busselman, Rachel E. and Meyers, Alyssa C. and Zecca, Italo B and Auckland, L. and Castro, Andres H and Dowd, Rebecca E and Curtis-Robles, R. and Hodo, C. and Saunders, A. and Hamer, S.}
}
Abstract
Canine Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is increasingly recognized as a health concern for dogs in the USA, and infected dogs may signal geographic regions of risk for human disease. Dogs living in multi-dog kennel environments (kennels with more than one dog) where triatomine vectors are endemic may be at high risk for infection. We monitored a cohort of 64 T. cruzi-infected and uninfected dogs across 10 kennels in Texas, USA, to characterize changes in infection status over one year. We used robust diagnostic criteria in which reactivity on multiple independent platforms was required to be considered positive. Among the 30 dogs enrolled as serologically- and/or PCR-positive, all but one dog showed sustained positive T. cruzi diagnostic results over time. Among the 34 dogs enrolled as serologically- and PCR-negative, 10 new T. cruzi infections were recorded over a 12-month period. The resulting incidence rate for dogs initially enrolled as T. cruzi-negative was 30.7 T. cruzi infections per 100 dogs per year. This study highlights the risk of T. cruzi infection to dogs in kennel environments. To protect both dog and human health, there is an urgent need to develop more integrated vector control methods as well as prophylactic and curative antiparasitic treatment options for T. cruzi infection in dogs.
